Disease dynamics in a coupled cholera model linking within-host and between-host interactions
نویسندگان
چکیده
منابع مشابه
Emerging disease dynamics in a model coupling within-host and between-host systems.
Epidemiological models and immunological models have been studied largely independently. However, the two processes (between- and within-host interactions) occur jointly and models that couple the two processes may generate new biological insights. Particularly, the threshold conditions for disease control may be dramatically different when compared with those generated from the epidemiological...
متن کاملA discrete-time analog for coupled within-host and between-host dynamics in environmentally driven infectious disease
In this paper, we establish a discrete-time analog for coupled within-host and between-host systems for an environmentally driven infectious disease with fast and slow two time scales by using the non-standard finite difference scheme. The system is divided into a fast time system and a slow time system by using the idea of limit equations. For the fast system, the positivity and boundedness of...
متن کاملCoupled within-host and between-host dynamics and evolution of virulence.
Mathematical models coupling within- and between-host dynamics can be helpful for deriving trade-off functions between disease transmission and virulence at the population level. Such functions have been used to study the evolution of virulence and to explore the possibility of a conflict between natural selection at individual and population levels for directly transmitted diseases (Gilchrist ...
متن کاملA mathematical model for coupling within-host and between-host dynamics in an environmentally-driven infectious disease.
This work presents a new model for the linking of within- and between-host dynamics. We use this as a conceptual model for the dynamics of Toxoplasma gondii, in which the parasite's life cycle includes interactions with the environment. We postulate the infection process to depend on the size of the infective inoculum that susceptible hosts may acquire by interacting with a contaminated environ...
متن کاملModeling Disease Dynamics at Within-Host and Between-Host Scales: HIV and Influenza as case studies
Mathematical models are becoming increasingly useful in studying the dynamics of infectious diseases, from within-host to between-host scales. With HIV and influenza as case studies, I will demonstrate how modeling can provide great insights into complex phenomena of these diseases. First, I will present a within-host model that can help address some of the issues related to the HIV-1 treatment...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Dynamics
سال: 2016
ISSN: 1751-3758,1751-3766
DOI: 10.1080/17513758.2016.1231850